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Publications
Feature Articles
1. H. Li, E. Shkolyar, J. Wang, S. Conti, A. C. Pao, J. C. Liao, T.-S. Wong and P. K. Wong, “SLIPS-LAB—A bioinspired bioanalysis system for metabolic evaluation of urinary stone disease”, Science Advances 6, eaba8535, 2020. Link 2. H. Li, P. Torab, P. K. Wong, “Detection of bacterial infection via a fidget spinner”, Nature Biomedical Engineering 4, 577–578, 2020. Link 3. H. Li, P. Torab, K. E. Mach, C. Surrette, M. R. England, D. W. Craft, N. J. Thomas, J. C. Liao, C. Puleo, and P. K. Wong, “Adaptable microfluidic system for single-cell pathogen classification and antimicrobial susceptibility testing”, Proceedings of the National Academy of Sciences of the United States of America 116 10270-10279, 2019. Link 4. R. Riahi, J. Sun, S. Wang, M. Long, D. D. Zhang, and P. K. Wong, “Notch1-Dll4 signaling and mechanical force regulate leader cell formation during collective cell migration” Nature Communications 6, 6556, 2015. Link 5. S. Wang, R. Riahi, N. Li, D. D. Zhang, and P. K. Wong, "Single Cell Nanobiosensors for Dynamic Gene Expression Profiling in Native Tissue Microenvironments", Advanced Materials 27, 6034-6038, 2015. Link
Archived Journal Publications
1. H. Li, E. Shkolyar, J. Wang, S. Conti, A. C. Pao, J. C. Liao, T.-S. Wong and P. K. Wong, “SLIPS-LAB—A bioinspired bioanalysis system for metabolic evaluation of urinary stone disease”, Science Advances 6, eaba8535, 2020. Link 2. H. Li, P. Torab, P. K. Wong, “Detection of bacterial infection via a fidget spinner”, Nature Biomedical Engineering 4, 577–578, 2020. Link 3. P. Torab*, Y. Yan*, H. Yamashita, J. I. Warrick, J. D. Raman, D. J. DeGraff, and P. K. Wong, “Three-Dimensional Microtumors for Probing Heterogeneity of Invasive Bladder Cancer” Analytical Chemistry 2020. Link 4. N. Zhu and P. K. Wong, “Advances in Viral Diagnostic Technologies for Combating COVID-19 and Future Pandemics”, SLAS Technology 2020. Link 5. S. Punj, D. Sidhu, D. Bhattacharya, M. Wang, and P. K. Wong, “An Electrochemical Biosensor Platform for Rapid Immunoanalysis of Physiological Fluids”, IEEE OJ Nano 1, 31-37, 2020. Link 6. J. Wang, L. Wang, N. Sun, R. Tierney, H. Li, M. Corsetti, L. Williams, P. K. Wong, and T.-S. Wong, “Viscoelastic solid-repellent coatings for extreme water saving and global sanitation”, Nature Sustainability 2, 1097–1105, 2019. Link 7. H. Li, P. Torab, K. E. Mach, C. Surrette, M. R. England, D. W. Craft, N. J. Thomas, J. C. Liao, C. Puleo, and P. K. Wong, “Adaptable microfluidic system for single-cell pathogen classification and antimicrobial susceptibility testing”, Proceedings of the National Academy of Sciences of the United States of America 116 10270-10279, 2019. Link 8. Y. Xiao, R. Riahi, P. Torab, D. D. Zhang, and P. K. Wong, “Collective Cell Migration in 3D Epithelial Wound Healing”, ACS NANO 13, 1204-1212, 2019. Link 9. H. Li, M. Morowitz, N. Thomas, and P. K. Wong, “Rapid Single Cell Microbiological Analysis – Toward Precision Management of Infections and Dysbiosis”, SLAS Technology 24, 603-605, 2019. Link 10. H. Yamashita, Y. Kawasawa, L. Shuman, Z. Zheng, T. Tran, V. Walter, J. Warrick, H. Al-Ahmadie, M. Kaag, P. K. Wong, J. Raman, G. Chen, and D. DeGraff, “Repression of Transcription Factor AP-2 Alpha by PPARγ Reveals a Novel Transcriptional Circuit in Basal-squamous Bladder Cancer”, Oncogenesis 8, 69, 2019. Link 11. H. Li, T. Garner, F. Diaz, and P. K. Wong, “A Multiwell Microfluidic Device for Analyzing and Screening Nonhormonal Contraceptive Agents”, Small, 15, 1901910, 2019. Link 12. F. Bocci*, S. C. Tripathi*, S A Vilchez Mercedes*, J. T. George, J. P Casabar, P. K. Wong, S. M. Hanash, H. Levine, J. N. Onuchic, M. K. Jolly, “NRF2 activates a partial Epithelial-Mesenchymal Transition and is maximally present in a hybrid Epithelial/Mesenchymal phenotype”, Integrative Biology 11, 251-263, 2019. Link 13. J. Gao, H. Li, P. Torab, K. E. Mach, D. W. Craft, N. J. Thomas, C. M. Puleo, J. C. Liao, T.-H. Wang, and P. K. Wong, “Nanotube Assisted Microwave Electroporation for Single Cell Pathogen Identification and Antimicrobial Susceptibility Testing”, Nanomedicine: Nanotechnology, Biology, and Medicine 17, 246-253, 2019. Link 14. Y. Wan, N. Zhu, Y. Lu, and P. K. Wong, “A DNA Transformer for Visualizing Endogenous RNA Dynamics in Live Cells”, Analytical Chemistry 91, 2626-2633, 2019. Link 15. N. Jamilpour, K.-H. Nam, C. Gregorio, and P, K. Wong, “Probing Collective Mechanoadaptation in Cardiomyocyte Development by Plasma Lithography Patterned Elastomeric Substrates”, ACS Biomaterials Science and Engineering 5, 3808-3816, 2019. Link 16. K. E. Mach, A. M. Kaushik, K. Hsieh, P. K. Wong, T.-H. Wang, J. C. Liao, “Optimizing Peptide Nucleic Acid Probes for Hybridization-based Detection and Identification of Bacterial Pathogens” Analyst 144, 1565-1574, 2019. Link 17. Z. S. Dean, N. Jamilpour, M. J. Slepian, and P. K. Wong, “Decreasing Wound Edge Stress Enhances Leader Cell Formation during Collective Smooth Muscle Cell Migration” ACS Biomaterials Science and Engineering 5, 3864-3875, 2019. Link 18. S. Wang, Y. Xiao, D. D. Zhang, and P. K. Wong, “A Gapmer Aptamer Nanobiosensor for Real-time Monitoring of Transcription and Translation in Single Cells”, Biomaterials 156, 56-64, 2018. Link 19. H. Li, Y. Lu, P. K. Wong, “Diffusion-reaction kinetics of microfluidic amperometric biosensors”, Lab on a Chip 18, 2086, 2018. Link 20. M. Chu, S. Novak, C. Cover, A. Wang, I. Chinyere, E. Juneman, D. Zarnescu, P. K. Wong, and Carol Gregorio, “Increased cardiac arrhythmogenesis associated with gap junction remodeling with upregulation of RNA binding protein FXR1”, Circulation 137, 605-618, 2018. Link 21. M. Dodson, P. Liu, T. Jiang, A. J. Ambrose, G. Luo, M. Rojo de la Vega, A. B. Cholanians, P. K. Wong, E. Chapman, and D. D. Zhang, “Increased O-GlcNAcylation of SNAP29 Drives Arsenic-Induced Autophagic Dysfunction”, Molecular and Cellular Biology 38, e00595-17, 2018. Link 22. G. B. Kim, Y. Chen, W. Kang, J. Guo, R. Payne, H. Li, Q. Wei, J. Baker, C. Dong, S. Zhang, P. K. Wong, E. B. Rizk, J. Yan, J. Yang, “The critical chemical and mechanical regulation of folic acid on neural engineering”, Biomaterials 178, 504-516, 2018. Link 23. Z. Wang and P. K. Wong, “Development of DNA Pair Biosensor for Quantization of Nuclear Factor Kappa B”, Biosensors 8, 126, 2018. Link 24. C. Surrette, B. Scherer, A. Corwin, G. Grossmann, A. M. Kaushik, K. Hsieh, P. Zhang, J. C. Liao, P. K. Wong, T. H. Wang, and C. M. Puleo, “Rapid Microbiology Screening in Pharmaceutical Workflows”, SLAS Technology 23, 387-394, 2018. Link 25. M. Dodson, M. Rojo de la Vega, B. Harder, R. Castro-Portuguez, S. D. Rodrigues, P. K. Wong, E. Chapman, D. D. Zhang. Low-level arsenic causes proteotoxic stress and not oxidative stress. Toxicology and Applied Pharmacology 341, 106-113, 2018. Link 26. Y. Sun, D.-J. Kim, and P. K. Wong, “Advancing Mechanobiology by Micro/Nanosystems”, IEEE Transactions on Nanotechnology 17, 371, 2018. Link 27. E. Altobelli, R. Mohan, K. E. Mach, M. L. Y. Sin, V. Anikst, M. Buscarini, P. K. Wong V. Gau, N. Banaei, J., C. Liao, “Integrated Biosensor Assay for Rapid Uropathogen Identification and Phenotypic Antimicrobial Susceptibility Testing”, European Urology Focus 3, 293-299, 2017. Link 28. S. Wang, J. Sun, Y. Xiao, Y. Lu, D. D. Zhang, and P. K. Wong, “Intercellular Tension Negatively Regulates Angiogenic Sprouting of Endothelial Tip Cells via Notch1-Dll4 Signaling” Advanced Biosystems, 1600019, 2017. Link Mov1 29. J. Gao, L. Jeffries, K. E. Mach, D. W. Craft, N. J. Thomas, V. Gau, J. C. Liao, and P. K. Wong, “A Multiplex Electrochemical Biosensor for Bloodstream Infection Diagnosis”, SLAS Technology 22, 466-474 (2017). Link 30. E. M. K. K. Hewage, D. Spear, T. M. Umstead, S. Hu, M. Wang, P. K. Wong, Z. C. Chroneos, E. S. Halstead, and N. J. Thomas, “An Electrochemical Biosensor for Rapid Detection of Pediatric Bloodstream Infections”, SLAS Technology 22, 616-625, 2017. Link 31. S. Wang, J. Sun, D. D. Zhang, and P. K. Wong, “A Nanobiosensor for Dynamic Single Cell Analysis during Microvascular Self-Organization” Nanoscale 8, 16894-16901, 2016. Link PDF 32. Z. S. Dean, P. Elias, N. Jamilpour, U. Utzinger, and P. K. Wong, “Probing 3D collective cancer invasion using double-stranded locked nucleic acid biosensors” Analytical Chemistry 88, 8902-8907, 2016. Link PDF 33. M. Long, M. R. de la Vega, Q. Wen, M. Bharara, T. Jiang, R. Zhang, S. Zhou, P. K. Wong, G. T. Wondrak, H. Zheng, and D. D. Zhang, “An essential role of NRF2 in diabetic wound healing” Diabetes 65, 780-793, 2016. Link 34. J. Sun, J. B. Hoying, P. A. Deymier, D. D. Zhang, and P. K. Wong, “Cellular Architecture Regulates Collective Calcium Signaling and Cell Contractility” PLoS Computational Biology 12, e1004955, 2016. Link 35. Y. Yang, N. Jamilpour, B. Yao, Z. S. Dean, R. Riahi and P. K. Wong, “Probing Leader Cells in Endothelial Collective Migration by Plasma Lithography Geometric Confinement”, Scientific Reports 6, 22707, 2016. Link 36. Y. Lu, Q. Ren, T. Liu, S. L. Leung, V. Gau, J. C. Liao, C. L. Chan, P. K. Wong, “Long-range electrothermal fluid motion in microfluidic systems”, International Journal of Heat and Mass Transfer 98, 341-349, 2016. Link 37. Y. Xiao, Y. Lu, M. Hsieh, J. C. Liao, and P. K. Wong, “A Microfiltration Device for Urogenital Schistosomiasis Diagnostics” PLoS ONE 11, e0154640, 2016. Link 38. Q. Tang, M. Liang, Y. Lu, P. K. Wong, G. J. Wilmink, D. Zhang, H. Xin, “Microfluidic Devices for Terahertz Spectroscopy of Live Cells Toward Lab-on-a-Chip Applications. Sensors 16, 476, 2016.” Link 39. R. Riahi, J. Sun, S. Wang, M. Long, D. D. Zhang, and P. K. Wong, “Notch1-Dll4 signaling and mechanical force regulate leader cell formation during collective cell migration” Nature Communications 6, 6556, 2015. Link PDF SI 40. S. Wang, R. Riahi, N. Li, D. D. Zhang, and P. K. Wong, "Single Cell Nanobiosensors for Dynamic Gene Expression Profiling in Native Tissue Microenvironments", Advanced Materials 27, 6034-6038, 2015. Link PDF 41. C. T. Pappas, R. M. Mayfield, C. Henderson, N. Jamilpour, C. Cover, Z. Hernandez, K. R. Hutchinson, M. Chu, K.-H. Nam, J. M. Valdez, P. K. Wong, H. L. Granzier, and C. C. Gregorio, “Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality”, Proceedings of the National Academy of Sciences of the United States of America 112, 13573-13578, 2015. Link PDF 42. Y. Lu, D. Macias, Z. S. Dean, N. R. Kreger, and P. K. Wong, “A UAV-Mounted Whole Cell Biosensor System for Environmental Monitoring Applications”, IEEE Transactions on Nanobioscience 15, 811-817m 2015. Link PDF 43. K. Mach, R. Mohan, S. Patel, P. K. Wong, M. Hsieh, J. C. Liao, “Development of a biosensor-based rapid urine test for detection of urogenital schistosomiasis”, PLOS Neglected Tropical Diseases e0003845, 2015. Link PDF 44. T. Jiang, B. Harder, M. Rojo de la Vega, P. K. Wong, E. Chapman, and D. D. Zhang, "p62 links autophagy and Nrf2 signaling", Free Radical Biology & Medicine 88, 199-204, 2015. Link PDF 45. Y. Lu, T. Liu, A. C. Lamanda, M. L. Y. Sin, V. Gau, J. C. Liao, and P. K. Wong, “AC Electrokinetics of Physiological Fluids for Biomedical Applications” Journal of Laboratory Automation 20, 611-620, 2015. Link PDF 46. T. Wu, B. G. Harder, P. K. Wong, J. E. Lang, and D. D. Zhang, “Oxidative Stress, Mammospheres and Nrf2 – New Implication for Breast Cancer Therapy” Molecular Carcinogenesis 54, 1494-1502, 2015. Link PDF 47. K. R. Ammann, K. J. DeCook, P. L. Tran, V. M. Merkle, P. K. Wong, and M. J. Slepian, “Collective cell migration of smooth muscle and endothelial cells: impact of injury versus non-injury stimuli”, Journal of Biological Engineering 9:19, 2015. Link PDF 48. T. Shen, T. Jiang, M. Long, J. Chen, D. Ren, P. K. Wong, E. Chapman, B. Zhou, and D. D. Zhang, “ A curcumin derivative that inhibits vinyl carbamate-induced lung carcinogenesis via activation of the Nrf2 protective response”, Antioxidants and Redox Signaling 23, 651-664, 2015. Link PDF 49. J. Sun, Y. Xiao, S. Wang, M. J. Slepian, and P. K. Wong, “Advances in techniques for probing mechanoregulation of tissue morphogenesis” Journal of Laboratory Automation 20, 127-137, 2015. Link PDF 50. Z. Dean, R. Riahi, P. K. Wong, “Spatiotemporal dynamics of microRNA during epithelial collective cell migration” Biomaterials 37, 156-163, 2015. PDF 51. S. Tao, S. Wang, S. J. Moghaddam, A. Ooi and E. Chapman, P. K. Wong and D. D. Zhang, “Oncogenic KRAS confers chemoresistance by transcriptional upregulation of NRF2 via the TPA Response Element” Cancer Research 74, 7430-7441, 2014. PDF 52. T. Wu, F. Zhao, B. Gao, C. Tan, N. Yagishita, T. Nakajima, P. K. Wong, E. Chapman, D. Fang, and D. D. Zhang. “Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis” Genes & Development 28, 708-722, 2014. PDF 53. K.-H. Nam, N. Jamilpour, E. Mfoumou, F.-Y. Wang, D. D. Zhang, and P. K. Wong, “Probing Mechanoregulation of Neuronal Differentiation by Plasma Lithography Patterned Elastomeric Substrates” Scientific Reports 4, 6965, 2014. PDF 54. R. Riahi, S. Wang, M. Long, N. Li, P.-Y. Chiou, D. D. Zhang, and P. K. Wong, “Mapping Photothermally Induced Gene Expression in Living Cells and Tissues by Nanorod-Locked Nucleic Acid Complexes” ACS Nano 8, 3597-3605, 2014. PDF 55. T. Liu, Y Lu, V. Gau, J. C. Liao, and P. K. Wong, “Rapid antimicrobial susceptibility testing with electrokinetics enhanced biosensors for diagnosis of acute bacterial infections” Annals of Biomedical Engineering 42, 2314-2321, 2014. PDF 56. J. Sun, N. Jamilpour, F.-Y. Wang, and P. K. Wong, “Geometric Control of Capillary Architecture via Cell-Matrix Mechanical Interactions”, Biomaterials 35, 3273-3280, 2014. PDF 57. T. Liu, M. L. Y. Sin, J. D. Pyne, V. Gau, J. C. Liao, and P. K. Wong, “Electrokinetic Stringency Control in Self-Assembled Monolayer-based Biosensors for Multiplex Urinary Tract Infection Diagnosis”, Nanomedicine: Nanotechnology, Biology, and Medicine 10, 159-166, 2014. PDF 58. M. L. Y. Sin, K. E. Mach, P. K. Wong, and J. C. Liao, “Advances and challenges in biosensor-based diagnosis of infectious diseases”, Expert Review of Molecular Diagnostics 2, 225-244, 2014. PDF 59. R. Riahi, M. Long, Y. Yang, Z Dean, D. D. Zhang, M. J. Slepian, and Pak Kin Wong, “Single Cell Gene Expression Analysis in Injury-Induced Collective Cell Migration”, Integrative Biology 6, 192-202, 2014. PDF 60. M. W. Kadlec, D. You, J. C. Liao, and P. K. Wong, “A cell phone-based microphotometric system for rapid antimicrobial susceptibility testing”, Journal of Laboratory Automation 19, 258-266, 2014. PDF 61. R. Riahi Y. L. Yang, H. Kim, L. Jiang, P. K. Wong, and Y. Zohar. “A microfluidic model for organ-specific extravasation of circulating tumor cells”, Biomicrofluidics 8, 024103, 2014. PDF 62. S. Tao, Y. Zheng, A. Lau, M. C. Jaramilo, B. T. Chau, C. R. Lantz, P. K. Wong, G. Wondrak, and D. D. Zhang, “Tanshinone l activates the Nrf2-dependent antioxidant response and protects against As(III)-induced lung inflammation in vitro and in vivo”, Antioxidants & Redox Signaling 19, 1647-1661, 2013. PDF 63. M. L. Y. Sin, V. Gau, J. C. Liao, and P. K. Wong, “A Universal Electrode Approach for Automated Electrochemical Molecular Analyses”, IEEE/ASME Journal of Microelectromechanical Systems 22, 1126-1132, 2013. PDF 64. R. Riahi, Z. Dean, T.-H. Wu, M. A. Teitell, P.-Y. Chiou, D. D. Zhang, and P. K. Wong, “Detection of mRNA in living cells by double-stranded locked nucleic acid probes”, Analyst 138, 4777-4785, 2013. PDF 65. M. Ouyang, R. Mohan, Y. Lu, T. Liu, K. E. Mach, M. L. Y. Sin, M. McComb, J. Joshi, V. Gau, P. K. Wong, J. C. Liao, “AC Electrokinetics Facilitated Biosensor Cassette for Rapid Pathogen Identification”, Analyst 138, 3660-3666, 2013. PDF 66. Y. Lu, J. Gao, D. D. Zhang, V. Gau, J. C. Liao, and P. K. Wong, “Single cell antimicrobial susceptibility testing by confined microchannels and electrokinetic loading”, Analytical Chemistry 85, 3971-3976, 2013. PDF 67. M. Junkin, Yi Lu, J. Long, P. Deymier, J. Hoying, and P. K. Wong, "Mechanically Induced Intercellular Calcium Communication in Confined Endothelial Structures", Biomaterials 34, 2049-2056, 2013. PDF 68. F.-Y. Wang and P. K. Wong, “Intelligent Systems and Technology for Integrative and Predictive Medicine: An ACP Approach”, ACM Transactions on Intelligent Systems and Technology 4, No. 32, 2013. PDF 69. M. L. Y. Sin, V. Gau, J. C. Liao, and P. K. Wong, “A Universal Electrode Approach for Molecular Diagnostics”, IEEE Nanotechnology Magazine 7, 31-37, 2013. PDF 70. J. Long*, M. Junkin*, P. K. Wong, J. Hoying, and P. Deymier, “Calcium Wave Propagation in Networks of Endothelial Cells: Model-based Theoretical and Experimental Study”, PLoS Computational Biology 8, e1002847, 2012. (* equal contribution) PDF 71. J. Gao, R. Riahi, M. L. Y. Sin, S. Zhang, and P. K. Wong, “Electrokinetic Focusing and Separation of Mammalian Cells in Conductive Biological Fluids”, Analyst 137, 5215-5221, 2012. (This paper is featured in the inside cover.) PDF 72. M. L. Y. Sin, T. Liu, J. D. Pyne, V. Gau, J. C. Liao, and P. K. Wong, “In situ electrokinetic enhancement for self-assembled monolayer based electrochemical biosensing”, Analytical Chemistry 84, 2702-2707, 2012. PDF 73. R. Riahi, Y. Yang, D. D. Zhang, and P. K. Wong, "Advances in Wound Healing Assays for Probing Collective Cell Migration" Journal of Association for Laboratory Automation 17, 59-65, 2012. PDF 74. M. Junkin, S. L. Leung, S. Whitman, C. C. Gregorio, and P. K. Wong, "Cellular Self-Organization via Autocatalytic Alignment Feedback", Journal of Cell Science 124, 4213-4220, 2011. (This paper is featured as the cover article and is highlight by the editor) PDF HIGHLIGHT 75. R. Riahi, K. Mach, R. Mohan, J. C. Liao, and P. K. Wong, "Molecular Detection of Bacterial Pathogens using Particle Enhanced Double-Stranded DNA Probes", Analytical Chemistry 83, 6349-6354, 2011. PDF 76. M. Junkin and P. K. Wong, "Probing Cell Migration in Confined Environments by Plasma Lithography", Biomaterials 32, 1848-1855, 2011. PDF 77. K. E. Mach, P. K. Wong, and J. C. Liao, "Biosensor Diagnosis of Urinary Tract Infections: A Path to Better Treatment?", Trends in Pharmacological Sciences 32, 330-336, 2011. PDF 78. J. Gao, M. L. Y. Sin, T. Liu, V. Gau, J. C. Liao, and P. K. Wong, " Hybrid Electrokinetic Manipulation in High-Conductivity Media", Lab on a Chip 11, 1770-1775, 2011. PDF 79. R. Mohan, K. E. Mach, M. Bercovici, P. K. Wong, and J. C. Liao, "Clinical validation of integrated nucleic acid and protein detection on an electrochemical biosensor array for urinary tract infection diagnosis", PLoS ONE 6, e26846, 2011. PDF 80. Y. Yang, J. Volmering, M. Junkin, and P. K. Wong, "Comparative Assembly of Colloidal Quantum Dots on Surface Templates Patterned by Plasma Lithography, Soft Matter 7, 10085-10090, 2011. PDF 81. H. Zheng, S. A. Whitman, W. Wu, G. Wondrak, P. K. Wong, D. Fang, and D. D. Zhang, "Therapeutic Potential of Nrf2 Activators in Streptozotocin-Induced Diabetic Nephropathy", Diabetes 60, 3055-3066, 2011. PDF 82. K. E. Mach, R. Mohan, E. J. Baron, M.-C. Shih, V. Gau, P. K. Wong, and J. C. Liao, “A Versatile Biosensor Platform for Rapid Antimicrobial Susceptibility Testing Directly from Clinical Samples”, Journal of Urology 185, 148-153. 2011. PDF 83. M. Junkin, S. L. Leung, Y. Yang, Y. Lu, J. Volmering, and P. K. Wong, " Plasma lithography surface patterning for creation of cell networks", Journal of Visualized Experiments 52, 2011. Link 84. M. L. Y. Sin, J. Gao, J. C. Liao and P. K. Wong, "System Integration - A Major Step Toward Lab on a Chip", Journal of Biological Engineering 5:6, 2011. PDF 85. S. Choi, M. Goryll, M. L. Y. Sin, P. K. Wong, and J. Chae, “Microfluidic-Based Biosensor toward Point-of-care Detection of Nucleic Acids and Proteins”, Microfluidics and Nanofluidics 10, 231-247, 2011. PDF 86. C. H. Chen, V. Gau, D. D. Zhang, J. C. Liao, Fei-Yue Wang, and P. K. Wong, “Statistical Metamodeling for Revealing Synergistic Antimicrobial Interactions”, PLoS ONE 5, e15472, 2010. PDF 87. Chia Hsiang Chen, Yi Lu, Mandy L. Y. Sin, Kathleen E. Mach, Donna D. Zhang, Vincent Gau, Joseph C. Liao, and Pak Kin Wong, “Antimicrobial Susceptibility Testing Using High Surface-to-Volume Ratio Microchannels”, Analytical Chemistry 8, 1012-1019, 2010. PDF 88. M. L. Y. Sin, V. Gau, J. C. Liao, and P. K. Wong, “Electrothermal Fluid Manipulation of High-Conductivity Samples for Laboratory Automation Applications”, Journal of Association for Laboratory Automation 15, 426-432, 2010. PDF 89. Y. Pan, G. A. Sonn, M. L. Y. Sin, K. E. Mach, M.-C. Shih, V. Gau, P. K. Wong, and J. C. Liao, “Electrochemical Immunosensor Detection of Urinary Lactoferrin in Clinical Samples for Urinary Tract Infection Diagnosis”, Biosensors and Bioelectronics 26, 649-654, 2010. PDF 90. May L. Chiu, Walson Lawi, Steven T. Snyder, Pak Kin Wong, Joseph Liao, and Vincent Gau, “Matrix Effects – A Challenge Toward Automation of Molecular Analysis”, Journal of the Association for Laboratory Automation 15, 233-242, 2010. PDF 91. N. Li, and P. K. Wong, “Transfection of Molecular Beacons in Microchannels for Single Cell Gene Expression Analysis”, Bioanalysis 2, 1689-1699, 2010. PDF 92. Tza-Huei Wang and Pak Kin Wong, “Transforming Microfluidics into Laboratory Automation”, Journal of the Association for Laboratory Automation, 15, A15-16, 2010. PDF 93. Deok-Ho Kim, Pak Kin Wong, Jungyul Park, Andre Levchenko, and Yu Sun, "Microengineered Platforms for Cell Mechanobiology," Annual Review of Biomedical Engineering 11, 203-233, 2009. PDF 94. Michael Junkin, Jennifer Watson, Jonathan P. Vande Geest, and Pak Kin Wong, “Template-Guided Self-Assembly of Colloidal Quantum Dots using Plasma Lithography”, Advanced Materials 21, 1247-1251, 2009. PDF 95. Mandy L. Y. Sin, Vincent Gau, Joseph C. Liao, David A. Haake, and Pak Kin Wong, “Active Manipulation of Quantum Dots Using AC Electrokinetics", Journal of Physical Chemistry C 113, 6561-6565, 2009. PDF 96. Fei Zhao, Tongde Wu, Alexandria Lau, Tao Jiang, Zheping Huang, Xiao-Jun Wang, Weimin Chen, Pak Kin Wong, Donna D. Zhang, “Nrf2 promotes neuronal cell differentiation”, Free Radical Biology and Medicine 47, 867-879, 2009. PDF 97. Walson Lawi, Chris Wiita, Steven T. Snyder, Fang Wei, avid Wong, Pak Kin Wong, Joseph C. Liao, David Haake, Vincent Gau, “A Microfluidic Cartridge System for Multiplexed Clinical Analysis”, Journal of the Association for Laboratory Automation 14, 407-412, 2009. PDF 98. Joseph Keyes, Michael Junkin, Pak Kin Wong, Jonathan P. Vande Geest, “Computational Simulation of a Magnetic Microactuator for Tissue Engineering Applications”, Biomedical Microdevices 11, 1259-1267, 2009. PDF 99. Vinay Gidwani, Reza Riahi, Donna D. Zhang, and Pak Kin Wong, “Hybridization Kinetics of Double-Stranded DNA Probes for Rapid Molecular Analysis”, Analyst 134, 1675-1681, 2009. (This paper is featured as the cover article) PDF 100. Jungkyu Kim., Michael Junkin, Deok-Ho Kim, Seugnlee Kwon, Young Shik Shin, Pak Kin Wong, and Bruce K. Gale, “Applications, Techniques, and Microfluidic Interfacing for Nanoscale Biosensing”, Microfluidics and Nanofluidics 7, 149-167, 2009. PDF 101. Mandy L. Y. Sin, Yusuke Shimabukuro, and Pak Kin Wong, “Hybrid Electrokinetics for Separation, Mixing, and Concentration of Colloidal Particles", Nanotechnology 20 165701, 2009. PDF 102. Joseph C. Liao, and Pak Kin Wong, “Nanotechnology and Prostate Cancer”, AUA News 13, 5-6, 2008 (invited article). PDF 103. Pak Kin Wong, Fu Yu, Arash Shahangian, Genhong Cheng, Ren Sun, and Chih-Ming Ho, "Closed-Loop Control of Cellular Functions using a Stochastic Search Algorithm," Proceedings of the National Academy of Sciences 105, 5105-5110, 2008. (This paper is featured in numerous news highlights including Eureka, Science Daily) PDF 104. Alexandria Lau, Nicole F. Villeneuve, Zheng Sun, Pak Kin Wong, Donna D. Zhang, “Dual roles of Nrf2 in cancer”, Pharmacological Research 58, 262-270, 2008. PDF 105. Joseph Keyes, Michael Junkin, Joseph Cappello, Xiaoyi Wu, and Pak Kin Wong, “Evaporation-induced assembly of biomimetic polypeptides,” Appl. Phys. Lett. 93, 023120, 2008. (This paper is selected for publication in the Virtual Journal of Nanoscale Science & Technology and in the Virtual Journal of Biological Physics Research) PDF 106. Daniel Meserve, Zhaohui Wang, Donna D. Zhang, and Pak Kin Wong, "A double-stranded molecular probe for homogeneous nucleic acid analysis," Analyst 133, 1313-1319, 2008. (This paper is selected for publication in the RSC’s Chemical Biology Research Article Virtual Journal) PDF 107. Xiao-Jun Wang, Zheng Sun, Nicole F. Villeneuve, Shirley Zhang, Fei Zhao, Yanjie Li, Weimin Chen, Xiaofang Yi, Wenxin Zheng, Georg T. Wondrak, Pak Kin Wong, and Donna D. Zhang, "Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2," Carcinogenesis 29, 1235-1243, 2008. PDF 108. Zhaohui Wang, Vinay Gidwani, Donna D. Zhang and Pin Kin Wong, “Separation-free detection of nuclear factor kappa B with double-stranded molecular probes”, Analyst 133, 998-1000, 2008. (Cover article) (This paper is selected for publication in the RSC’s Chemical Biology Research Article Virtual Journal) PDF 109. Yu Du, Nicole F. Villeneuve, Xiao-Jun Wang, Zheng Sun, Weimin Chen, Jixue Li, Hongxiang Lou, Pak Kin Wong, and Donna D. Zhang, "Oridonin confers protection against arsenic induced toxicity through activation of the Nrf2-mediated defensive response," Environmental Health Perspectives 116, 1154-1161, 2008. PDF 110. Zhaohui Wang, Vinay Gidwani, Zheng Sun, D. D. Zhang, and P. K. Wong, "Development of a molecular assay for rapid screening of chemopreventive compounds targeting Nrf2," Journal of the Association for Laboratory Automation 13, 243-248, 2008. PDF 111. Pak Kin Wong and Dean Ho, "Emergent Diagnostic and Therapeutic Platforms for Nanoengineered Medicine," IEEE Nanotechnology Magazine 2, 9-13, 2008. PDF 112. Pak Kin Wong, Winny Tan, Chih-Ming Ho, "Cell Relaxation after Electrodeformation: Effect of Latrunculin A on Actin Cytoskeleton", Journal of Biomechanics 38, 529-535, 2005. PDF 113. Tza-Huei Wang, Yahui Peng, Chunyang Zhang, Pak Kin Wong, Chih-Ming Ho, "Single-Molecule Tracing on a Fluidic Microchip for Quantitative Detection of Low-Abundance Nucleic Acids", Journal of American Chemical Society 127, 5354-5359, 2005. (Highlighted in Nanozone news in Nature, April 28, 2005) PDF 114. Pak Kin Wong, Che-Yang Chan, Tza-Huei Wang and Chih-Ming Ho "Electrokinetic Bioprocessor for Concentrating Cells and Molecules", Analytical Chemistry 76, 6908-6914, 2004. (This work has been highlighted in NIH NIDCR website) PDF 115. Pak Kin Wong, Tza-Huei Wang, Joanne H. Deval, Chih-Ming Ho, "Electrokinetics in Micro Devices for Biotechnology Applications", IEEE/ASME Transactions on Mechatronics 9, 366-376, 2004. PDF 116. Pak Kin Wong, Umberto Ulmanella and Chih-Ming Ho, "Fabrication of Microsurgical Tools for Single Cell Intracytoplasmic Injection", Journal of Microelectromechanical System 6, 940-946, 2004. PDF 117. Tzung K. Hsiai, Sung K. Cho, Pak K. Wong, Michael H. Ing, Adler Salazar, Susan Hama, Mohamad Navab, Linda L. Demer, Chih-Ming Ho, "Micro Sensors: Linking Real-Time Oscillatory Shear Stress with Vascular Inflammatory Responses", Annals of Biomedical Engineering 32, 189-201, 2004. PDF 118. Pak Kin Wong, Yi-Kuen Lee, Chih-Ming Ho, "Deformation of DNA Molecules by Hydrodynamic Focusing", Journal of Fluid Mechanics 497, 55-65, 2003. PDF 119. Tzung K. Hsiai, Sung K. Cho, Pak K. Wong, Michael Ing, Adler Salazar, Alex Sevanian, Mohamad Navab, Linda L. Demer, Chih-Ming Ho, "Monocyte Recruitment to Endothelial Cells in Response to Oscillatory Shear Stress", Federation of American Societies for Experimental Biology Journal 17, 1648-1657, 2003. PDF 120. Tzung K. Hsiai, Michael Ing, Juliana Hwang, Adler Salazar, Sung K. Cho, Pak Wong, Chih-Ming Ho, Mohamad Navab, "Endothelial Cells: The Living Sensors and Actuators", International Journal of Nonlinear Sciences and Numerical Simulation 3, 169-172, 2002. PDF
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