Peter Butler

Assessing the transport of nanoparticles to vascular endothelium in disturbed flow regions (Cellular Mechanobiology Laboratory)

Project Description: Students will use a newly developed flow chamber that simulates the disturbed laminar flow regions near blood vessel bifurcations. They will seed flow with nanoparticles to assess whether nanoparticles can be targeted to endothelium in these flow regions. Because diseased blood vessels typically occur in these regions, this work will provide the foundations for nanoparticle-based drug delivery to diseased vascular endothelium.

Group Research Website »


Contact Information

  • Keefe Manning, Ph.D.
    Professor of Biomedical Engineering and Surgery
  • Lacy Alexander, Ph.D.
    Associate Professor of Kinesiology

Faculty Research



The Department of Biomedical Engineering administers the bachelor of science, master of science, and doctorate degree programs in biomedical engineering. Our work combines traditional engineering principles with medicine and technology for the betterment of human health and society. 

Department of Biomedical Engineering

122 Chemical and Biomedical Engineering Building

The Pennsylvania State University

University Park, PA 16802-4400

Phone: 814-863-6614