Musculoskeletal Regenerative Engineering Laboratory

The Musculoskeletal Regenerative Engineering Lab focuses on understanding the fundamental mechanisms by which biomaterial interfaces alter the proliferation, migration, and differentiation of mesenchymal stem cells to guide the design of biomaterial scaffolds and facilitate the generation or regeneration of musculoskeletal tissues.

Current research in the lab involves the investigation of the interface between osteoprogenitor cells and synthetic nanofibers. Such as: the application of systems biology to elucidate the alterations in the interactome of an osteoprogenitor on nanofiber substrates as the cell population progresses from adhesion, to migration and proliferation, and finally differentiation; and also the utilization of polymer chemistry to modulate the diameter of synthetic nanofibers across several orders of magnitude and evaluate the subsequent alterations and interactions of focal adhesion proteins.

Contact Information

Bioengineering Facilities and Labs Bioengineering and biomedical engineering research areas


The Department of Biomedical Engineering administers the undergraduate major in biomedical engineering, and is a part of the university-wide Intercollege Graduate Degree Program, offering both M.S. and Ph.D. degrees in Bioengineering. Our work combines traditional engineering principles with medicine and technology for the betterment of human health and society. 

Department of Biomedical Engineering

122 Chemical and Biomedical Engineering Building

The Pennsylvania State University

University Park, PA 16802-4400

Phone: 814-863-6614