Probing brain networks in awake rodents

Abstract: Resting-state functional magnetic resonance imaging (rsfMRI) provides measurement of functional connectivity between brain regions. It represents a powerful tool to characterize the organizational architecture of whole-brain networks. However, several intrinsic issues have limited the potential of rsfMRI from being fully realized. In this presentation I will discuss these issues, and demonstrate that they can be partially solved by integrating rsfMRI with neuromodulation techniques such as optogenetics/chemogenetics in rodent models.

Bio:  Dr. Nanyin Zhang is Professor of Biomedical Engineering and Electrical Engineering at the Pennsylvania State University. His work has been focused on neuroimaging methods and applications. His lab has established a platform that integrates neuroimaging, electrophysiology, optogenetics, chemogenetics, and behavioral methods in rodent models. This platform provides multi-dimensional, multi-scale information in the same awake animals. These multi-modal approaches have significantly advanced the field in translational studies of animal models.

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Media Contact: Lisa Spicer



The Department of Biomedical Engineering administers the undergraduate major in biomedical engineering, and is a part of the university-wide Intercollege Graduate Degree Program, offering both M.S. and Ph.D. degrees in Bioengineering. Our work combines traditional engineering principles with medicine and technology for the betterment of human health and society. 

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