Photo of Sri-Rajasekhar (Raj) Kothapalli

Sri-Rajasekhar (Raj) Kothapalli

Assistant Professor of Biomedical Engineering


  • Biomedical Engineering
  • Center for Acoustics and Vibration
  • Acoustics

325 Chemical and Biomedical Engineering Building


Personal or Departmental Website




  • BS, Math, Physics, Chemistry, Nagarjuna University, 1995
  • MS, Nuclear Physics, Andhra University, 1997
  • M Phil, Condensed Matter Physics, University of Hyderabad, 1998
  • M.Eng, Applied Optics, I.I.T Delhi, 2000
  • MS, Applied Physics, University of Massachusetts, Boston, 2004
  • Ph D, Biomedical Engineering, Washington University in St. Louis, 2009
  • Postdoctoral, Radiology, Stanford University, 2013



Journal Articles

  • Christopher Cheng and Sri-Rajasekhar Kothapalli, 2022, "Improving PMUT Receive Sensitivity via DC Bias and Piezoelectric Composition", Sensors, 22, (15)
  • Haoyang Chen and Sri-Rajasekhar Kothapalli, 2022, "A Transparent Ultrasound Array for Real-Time Optical, Ultrasound, and Photoacoustic Imaging", AAAS BME Frontiers, 2022
  • Shubham Mirg and Sri-Rajasekhar Kothapalli, 2022, "Awake mouse brain photoacoustic and optical imaging through a transparent ultrasound cranial window"
  • Sumit Agrawal and Sri-Rajasekhar Kothapalli, 2021, "Modeling Combined Ultrasound and Photoacoustic Imaging: Simulations aiding Device Development and Deep Learning", Photoacoustics, 24, pp. 100304
  • Haoyang Chen and Sri-Rajasekhar Kothapalli, 2021, "A High Sensitivity Transparent Ultrasound Transducer Based on PMN-PT for Ultrasound and Photoacoustic Imaging", IEEE Sensors Letters, 5, (11), pp. 1-4
  • Haoyang Chen and Sri-Rajasekhar Kothapalli, 2021, "A transparent low intensity pulsed ultrasound (LIPUS) chip for high-throughput cell stimulation", Lab on a Chip, 21, (24), pp. 4734-4742
  • Amirsaeed Yazdani and Sri-Rajasekhar Kothapalli, 2021, "Simultaneous Denoising and Localization Network for Photoacoustic Target Localization", IEEE Transactions on Medical Imaging, 40, (9), pp. 2367-2379
  • Ajay Dangi and Sri-Rajasekhar Kothapalli, 2019, "A Photoacoustic Imaging Device using Piezoelectric Micromachined Ultrasound Transducers (PMUTs)", IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

Conference Proceedings


Research Projects

  • September 2022 - August 2025, "Dual-modality Ultrasound and Photoacoustic Molecular Imaging Strategies for Lethal Prostate Cancer Detection," (Sponsor: Congressionally Directed Medical Research Programs).
  • September 2020 - May 2023, "A portable photoacoustic imager for diagnosing vascular diseases," (Sponsor: National Institute of Biomedical Imaging and Bioengineering).

Honors and Awards

  • NIH Pathway to Indepedence Grant Award K99/R00, National Institute of Health, May 2014 - June 2021
  • 2022 IEEE Sensors Letters Best Paper Award Runner-Up, IEEE Sensors Council, November 2022


Service to Penn State:

Service to External Organizations:




The Department of Biomedical Engineering administers the undergraduate major in biomedical engineering, and is a part of the university-wide Intercollege Graduate Degree Program, offering both M.S. and Ph.D. degrees in Bioengineering. Our work combines traditional engineering principles with medicine and technology for the betterment of human health and society. 

Department of Biomedical Engineering

122 Chemical and Biomedical Engineering Building

The Pennsylvania State University

University Park, PA 16802-4400

Phone: 814-863-6614