Photo of Daniel Hayes

Daniel Hayes

Associate Professor

Affiliation(s):

  • Biomedical Engineering

N242 Millennium Science Complex

djh195@psu.edu

814-865-0780

Personal or Departmental Website

Research Areas:

Nanomedicine and Drug Delivery; Tissue Engineering and Regenerative Medicine

 
 

 

Education

  • BS, Life Science, Penn State University, 1997
  • Ph D, Penn State University, 2004

Publications

Journal Articles

  • Caasy Thomas-Porch, Jie Li, Fabiana Zanata, Elizabeth C Martin, Nicholas Pashos, Kaylynn Genemaras, J Nicholas Poche, Nicholas P Totaro, Melyssa R Bratton, Dina Gaupp and Daniel Hayes, 2018, "Comparative proteomic analyses of human adipose extracellular matrices decellularized using alternative procedures", Journal of Biomedical Materials Research Part A, 106, (9), pp. 2481--2493
  • Mohammad Abu-Laban, Raju R Kumal, Jonathan Casey, Jeff Becca, Daniel LaMaster, Carlos Pacheco, Dan G Sykes, Lasse Jensen, Louis H Haber and Daniel Hayes, 2018, "Comparison of thermally actuated retro-diels-alder release groups for nanoparticle based nucleic acid delivery", Journal of colloid and interface science, 526, pp. 312--321
  • Anoosha Forghani, Leah Garber, Cong Chen, Fariborz Tavangarian, Timothy B Tighe, Ram Devireddy, John A Pojman and Daniel Hayes, 2018, "Fabrication and characterization of thiol-triacrylate polymer via Michael addition reaction for biomedical applications", Biomedical Materials, 14, (1), pp. 015001
  • Shue Li, John Nicholas Poche, Yiming Liu, Thomas Scherr, Jacob McCann, Anoosha Forghani, Mollie Smoak, Mitchell Muir, Lisa Berntsen, Cong Chen and Daniel Hayes, 2018, "Hybrid Synthetic-Biological Hydrogel System for Adipose Tissue Regeneration", Macromolecular bioscience, 18, (11), pp. 1800122
  • Raju R Kumal, Mohammad Abu-Laban, Prakash Hamal, Blake Kruger, Holden T Smith, Daniel Hayes and Louis H Haber, 2018, "Near-Infrared Photothermal Release of siRNA from the Surface of Colloidal Gold--Silver--Gold Core--Shell--Shell Nanoparticles Studied with Second-Harmonic Generation", The Journal of Physical Chemistry C, 122, (34), pp. 19699--19704
  • Wei Duan, Cong Chen, Masudul Haque, Daniel Hayes and Mandi J Lopez, 2018, "Polymer-mineral scaffold augments in vivo equine multipotent stromal cell osteogenesis", Stem cell research \& therapy, 9, (1), pp. 60
  • Pallab Datta, Aman Dhawan, Yin Yu, Daniel Hayes, Hemanth Gudapati and Ibrahim Ozbolat, 2017, "Bioprinting of osteochondral tissues: A perspective on current gaps and future trends", International Journal of Bioprinting, 3, (2), pp. 109--120
  • Colton McElheny, Daniel Hayes and Ram Devireddy, 2017, "Design and Fabrication of a Low-Cost Three-Dimensional Bioprinter", JOURNAL OF MEDICAL DEVICES-TRANSACTIONS OF THE ASME, 11, (4)
  • Mohammad Abu-Laban, Pranjali D. Muley, Daniel Hayes and Dorin Boldor, 2017, "Ex-situ up-conversion of biomass pyrolysis bio-oil vapors using Pt/Al2O3 nanostructured catalyst synergistically heated with steel balls via induction", CATALYSIS TODAY, 291, pp. 3-12
  • Anoosha Forghani, Lisa Kriegh, Katie Hogan, Cong Chen, Gabrielle Brewer, Timothy B. Tighe, Ram Devireddy and Daniel Hayes, 2017, "Fabrication and characterization of cell sheets using methylcellulose and PNIPAAm thermoresponsive polymers: A comparison Study", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 105, (5), pp. 1346-1354
  • Shahensha Shaik, Daniel Hayes, Jeffrey Gimble and Ram Devireddy, 2017, "Inducing Heat Shock Proteins Enhances the Stemness of Frozen-Thawed Adipose Tissue-Derived Stem Cells", STEM CELLS AND DEVELOPMENT, 26, (8), pp. 608-616
  • Marjorie E. Bateman, Amy L. Strong, Ryan S. Hunter, Melyssa R. Bratton, Rajesh Komati, Jayalakshmi Sridhar, Kevin E. Riley, Guangdi Wang, Daniel Hayes, Stephen M. Boue, Matthew E. Burow and Bruce A. Bunnell, 2017, "Osteoinductive effects of glyceollins on adult mesenchymal stromal/stem cells from adipose tissue and bone marrow", PHYTOMEDICINE, 27, pp. 39-51
  • Nicholas P Totaro, Zachari D Murphy, Abigail E Burcham, Connor T King, Thomas F Scherr, Christopher O Bounds, Vinod Dasa, John A Pojman and Daniel Hayes, 2016, "In vitro evaluation of thermal frontally polymerized thiol-ene composites as bone augments", Journal of Biomedical Materials Research Part B: Applied Biomaterials, 104, (6), pp. 1152–1160
  • Akanksha Kanitkar, Mollie Smoak, Cong Chen, Giovanna Aita, Thomas Scherr, Lee Madsen and Daniel Hayes, 2016, "Synthesis of novel polyesters for potential applications in skin tissue engineering", Journal of Chemical Technology & Biotechnology!!!, 91, (3), pp. 733–741
  • Raju R. Kumal, Mohammad Abu-Laban, Corey R. Landry, Blake Kruger, Zhenyu Zhang, Daniel Hayes and Louis H. Haber, 2016, "Plasmon-Enhanced Photocleaving Dynamics in Colloidal MicroRNA-Functionalized Silver Nanoparticles Monitored with Second Harmonic Generation", Langmuir, 32, (40), pp. 10394-10401
  • Sunting Xuan, Chang-Uk Lee, Cong Chen, Andrew B. Doyle, Yueheng Zhang, Li Guo, Vijay T. John, Daniel Hayes and Donghui Zhang, 2016, "Thermoreversible and Injectable ABC Polypeptoid Hydrogels: Controlling the Hydrogel Properties through Molecular Design", Chemistry of Materials, 28, (3), pp. 727-737
  • Raju R Kumal, Corey R Landry, Mohammad Abu-Laban, Daniel Hayes and Louis H Haber, 2015, "Monitoring the Photocleaving Dynamics of Colloidal MicroRNA-Functionalized Gold Nanoparticles Using Second Harmonic Generation", Langmuir, 31, (36), pp. 9983–9990
  • Maryam Rezai-Rad, Jonathan F Bova, Mahdi Orooji, Jennifer Pepping, Ammar Qureshi, Fabio Del Piero, Daniel Hayes and Shaomian Yao, 2015, "Evaluation of bone regeneration potential of dental follicle stem cells for treatment of craniofacial defects", Cytotherapy, 17, (11), pp. 1572–1581
  • Luis Alfaro, Daniel Hayes, Charles Boeneke, Zhimin Xu, David Bankston, Peter J Bechtel and Subramaniam Sathivel, 2015, "Physical properties of a frozen yogurt fortified with a nano-emulsion containing purple rice bran oil", LWT-Food Science and Technology, 62, (2), pp. 1184–1191
  • Mollie Smoak, Katie Hogan, Lisa Kriegh, Cong Chen, LeKeith B Terrell, Ammar T Qureshi, W Todd Monroe, Jeffrey M Gimble and Daniel Hayes, 2015, "Modulation of mesenchymal stem cell behavior by nano-and micro-sized $ß$-tricalcium phosphate particles in suspension and composite structures", Journal of Nanoparticle Research, 17, (4), pp. 182
  • Ammar T Qureshi, Andrew Doyle, Cong Chen, Diana Coulon, Vinod Dasa, Fabio Del Piero, Benjamin Levi, W Todd Monroe, Jeffrey M Gimble and Daniel Hayes, 2015, "Photoactivated miR-148b–nanoparticle conjugates improve closure of critical size mouse calvarial defects", Acta biomaterialia, 12, pp. 166–173
  • Cong Chen, Pilanda Watkins-Curry, Mollie Smoak, Katie Hogan, Steve Deese, Gregory T McCandless, Julia Y Chan and Daniel Hayes, 2015, "Targeting calcium magnesium silicates for polycaprolactone/ceramic composite scaffolds", ACS Biomaterials Science & Engineering, 1, (2), pp. 94–102
  • Akanksha Kanitkar, Cong Chen, Mollie Smoak, Katie Hogan, Thomas Scherr, Giovanna Aita and Daniel Hayes, 2015, "In vitro characterization of polyesters of aconitic acid, glycerol, and cinnamic acid for bone tissue engineering", Journal of biomaterials applications, 29, (8), pp. 1075–1085
  • AS Zanetti, GT McCandless, JY Chan, JM Gimble and DJ Hayes, 2015, "Characterization of novel akermanite: poly-?-caprolactone scaffolds for human adipose-derived stem cells bone tissue engineering", Journal of tissue engineering and regenerative medicine, 9, (4), pp. 389–404
  • Cong Chen, Leah Garber, Mollie Smoak, Carmel Fargason, Thomas Scherr, Caleb Blackburn, Sasha Bacchus, Mandi J Lopez, John A Pojman, Fabio Del Piero and others, 2014, "In vitro and In vivo characterization of pentaerythritol triacrylate-co-trimethylolpropane nanocomposite scaffolds as potential bone augments and grafts", Tissue Engineering Part A, 21, (1-2), pp. 320–331
  • Mollie Smoak, Cong Chen, Ammar Qureshi, Leah Garber, John A Pojman, Marlene E Janes and Daniel Hayes, 2014, "Antimicrobial cytocompatible pentaerythritol triacrylate-co-trimethylolpropane composite scaffolds for orthopaedic implants", Journal of Applied Polymer Science, 131, (22)
  • Bishnu P Regmi, Nicholas C Speller, Michael J Anderson, Jean Olivier Brutus, Yonathan Merid, Susmita Das, Bilal El-Zahab, Daniel Hayes, Kermit K Murray and Isiah M Warner, 2014, "Molecular weight sensing properties of ionic liquid-polymer composite films: theory and experiment", Journal of Materials Chemistry C, 2, (24), pp. 4867–4878
  • Jonathan C Dumke, Ammar Qureshi, Suzana Hamdan, Bilal El-Zahab, Susmita Das, Daniel Hayes, Dorin Boldor, Kresimir Rupnik and Isiah M Warner, 2014, "Photothermal response of near-infrared-absorbing nanoGUMBOS", Applied spectroscopy, 68, (3), pp. 340–352
  • Mark A Hoppens, Christopher B Sylvester, Ammar T Qureshi, Thomas Scherr, Desiree R Czapski, Randolph S Duran, Paul B Savage and Daniel Hayes, 2014, "Ceragenin mediated selectivity of antimicrobial silver nanoparticles", ACS applied materials & interfaces, 6, (16), pp. 13900–13908
  • Mark A Hoppens, Zaanan EW Wheeler, Ammar T Qureshi, Katie Hogan, Ashleigh Wright, George G Stanley, David Young, Paul Savage and Daniel Hayes, 2014, "Maghemite, silver, ceragenin conjugate particles for selective binding and contrast of bacteria", Journal of colloid and interface science, 413, pp. 167–174
  • Jonathan C Dumke, Ammar Qureshi, Suzana Hamdan, Kresimir Rupnik, Bilal El-Zahab, Daniel Hayes and Isiah M Warner, 2014, "In vitro activity studies of hyperthermal near-infrared nanoGUMBOS in MDA-MB-231 breast cancer cells", Photochemical & Photobiological Sciences, 13, (9), pp. 1270–1280
  • Andrea S Zanetti, Gregory T McCandless, Julia Y Chan, Jeffrey M Gimble and Daniel Hayes, 2014, "In vitro human adipose-derived stromal/stem cells osteogenesis in akermanite: poly-?-caprolactone scaffolds", Journal of biomaterials applications, 28, (7), pp. 998–1007
  • Ammar T Qureshi, Jace P Landry, Vinod Dasa, Marlene Janes and Daniel Hayes, 2014, "Can a novel silver nano coating reduce infections and maintain cell viability in vitro?", Journal of biomaterials applications, 28, (7), pp. 1028–1038
  • Ammar T Qureshi, Cong Chen, F Shah, Caasy Thomas-Porch, Jeffrey M Gimble and Daniel Hayes, 2014, "Human adipose-derived stromal/stem cell isolation, culture, and osteogenic differentiation.", Methods in enzymology, 538, pp. 67
  • Marsha R Cole, Min Li, Ravirajsinh Jadeja, Bilal El-Zahab, Daniel Hayes, Jeffery A Hobden, Marlene E Janes and Isiah M Warner, 2013, "Minimizing human infection from Escherichia coli O157: H7 using GUMBOS", Journal of Antimicrobial Chemotherapy, 68, (6), pp. 1312–1318
  • Paige K Brown, Ammar T Qureshi, Alyson N Moll, Daniel Hayes and W Todd Monroe, 2013, "Silver nanoscale antisense drug delivery system for photoactivated gene silencing", ACS nano, 7, (4), pp. 2948–2959
  • Leah Garber, Cong Chen, Kameron V Kilchrist, Christopher Bounds, John A Pojman and Daniel Hayes, 2013, "Thiol-acrylate nanocomposite foams for critical size bone defect repair: A novel biomaterial", Journal of Biomedical Materials Research Part A, 101, (12), pp. 3531–3541
  • Ammar T Qureshi, William T Monroe, Vinod Dasa, Jeffrey M Gimble and Daniel Hayes, 2013, "miR-148b–Nanoparticle conjugates for light mediated osteogenesis of human adipose stromal/stem cells", Biomaterials, 34, (31), pp. 7799–7810
  • Chengjun Zhou, Qingfeng Shi, Weihong Guo, Lekeith Terrell, Ammar T Qureshi, Daniel Hayes and Qinglin Wu, 2013, "Electrospun bio-nanocomposite scaffolds for bone tissue engineering by cellulose nanocrystals reinforcing maleic anhydride grafted PLA", ACS applied materials & interfaces, 5, (9), pp. 3847–3854
  • Thomas Scherr, Christian Quitadamo, Preston Tesvich, Daniel Sang-Won Park, Terrence Tiersch, Daniel Hayes, Jin-Woo Choi, Krishnaswamy Nandakumar and W Todd Monroe, 2012, "A planar microfluidic mixer based on logarithmic spirals", Journal of Micromechanics and Microengineering, 22, (5), pp. 055019
  • Bishnu P Regmi, Joshua Monk, Bilal El-Zahab, Susmita Das, Francisco R Hung, Daniel Hayes and Isiah M Warner, 2012, "A novel composite film for detection and molecular weight determination of organic vapors", Journal of Materials Chemistry, 22, (27), pp. 13732–13741
  • Marsha R Cole, Min Li, Bilal El-Zahab, Marlene E Janes, Daniel Hayes and Isiah M Warner, 2011, "Design, Synthesis, and Biological Evaluation of $ß$-Lactam Antibiotic-Based Imidazolium-and Pyridinium-Type Ionic Liquids", Chemical biology & drug design, 78, (1), pp. 33–41
  • Ammar T Qureshi, W Todd Monroe, Mandi J Lopez, Marlene E Janes, Vinod Dasa, Sunggook Park, Alborz Amirsadeghi and Daniel Hayes, 2011, "Biocompatible/bioabsorbable silver nanocomposite coatings", Journal of applied polymer science, 120, (5), pp. 3042–3053
  • Jonathan C Dumke, Bilal El-Zahab, Santhosh Challa, Susmita Das, Lin Chandler, Michael Tolocka, Daniel Hayes and Isiah M Warner, 2010, "Lanthanide-based luminescent nanoGUMBOS", Langmuir, 26, (19), pp. 15599–15603
  • Kalkan, A Kaan, Matthew R Henry, Handong Li, Joseph D Cuiffi, Daniel Hayes, Charles Palmer and Stephen J Fonash, 2005, "Biomedical/analytical applications of deposited nanostructured Si films", Nanotechnology, 16, (8), pp. 1383
  • Jeanna C Zguris, Laura J Itle, Daniel Hayes and Michael V Pishko, 2005, "Microreactor microfluidic systems with human microsomes and hepatocytes for use in metabolite studies", Biomedical microdevices, 7, (2), pp. 117–125
  • Joseph D Cuiffi, Daniel Hayes, Stephen J Fonash, Kwanza N Brown and Arthur D Jones, 2001, "Desorption- ionization mass spectrometry using deposited nanostructured silicon films", Analytical chemistry, 73, (6), pp. 1292–1295
  • Thomas J Hornyak, Daniel Hayes, Ling-Yu Chiu and Edward B Ziff, 2001, "Transcription factors in melanocyte development: distinct roles for Pax-3 and Mitf", Mechanisms of development, 101, (1), pp. 47–59
  • Thomas J Hornyak, Daniel Hayes and Edward B Ziff, 2000, "Cell-density-dependent regulation of expression and glycosylation of dopachrome tautomerase/tyrosinase-related protein-2", Journal of investigative dermatology, 115, (1), pp. 106–112
  • A Kaan Kalkan, Sanghoon Bae, Handong Li, Daniel Hayes and Stephen J Fonash, 2000, "Nanocrystalline Si thin films with arrayed void-column network deposited by high density plasma", Journal of Applied Physics, 88, (1), pp. 555–561

Conference Proceedings

  • TJ Hornyak, Daniel Hayes and EB Ziff, 1999, "Pax-3 as a proliferation factor for developing murine melanocytes", 112, (4), pp. 540–540

Other

Research Projects

  • January 2017 - December 2019, "Spatio-temporal Modulation of Osteogenesis in a 3-D Stromal Stem Cell Model," (Sponsor: National Institute of Dental and Craniofacial Research).

Honors and Awards

Service

Service to Penn State:

Service to External Organizations:

 


 

About

The Department of Biomedical Engineering administers the undergraduate major in biomedical engineering, and is a part of the university-wide Intercollege Graduate Degree Program, offering both M.S. and Ph.D. degrees in Bioengineering. Our work combines traditional engineering principles with medicine and technology for the betterment of human health and society. 

Department of Biomedical Engineering

122 Chemical and Biomedical Engineering Building

The Pennsylvania State University

University Park, PA 16802-4400

Phone: 814-863-6614