Photo of William Higgins

William Higgins

Distinguished Professor

Affiliation(s):

  • School of Electrical Engineering and Computer Science
  • Electrical Engineering
  • Biomedical Engineering

209F Electrical Engineering West

weh2@psu.edu

814-865-0186

Personal or Departmental Website

Lab Website

Research Areas:

Biomedical Devices and Systems; Computational Science; Data Science and Artificial Intelligence; Signal and Image Processing

Interest Areas:

3D Medical Image Processing, Virtual Endoscopy, Image Processing, Computer Vision, Visualization

 
 

 

Education

Publications

Book, Chapters

  • Trevor Kuhlengel and William E Higgins, 2019, Bronchoscopic procedure planning for systematic lymph node analysis
  • Wennan Zhao, Rebecca Bascom, Jennifer Toth and William E Higgins, 2019, Guidance System Development for Radial-Probe Endobronchial Ultrasound Bronchoscopy
  • Matthew McTaggart and William E Higgins, 2019, Robust Video-Frame Classification for Bronchoscopy
  • William E Higgins, Xiaonan Zang, Ronnarit Cheirsilp, Patrick Byrnes, Trevor Kuhlengel, Jennifer Toth and Rebecca Bascom, 2018, Optimal Multimodal Virtual Bronchoscopy for Convex-Probe Endobronchial Ultrasound, pp. 1057618-1 --- 1057618-6
  • William E Higgins and Patrick Byrnes, 2017, System for Endobronchial-Video Analysis
  • William E Higgins, Xiaonan Zang, Ronnarit Cheirsilp, Patrick Byrnes, Trevor Kuhlengel, Rebecca Bascom and Jennifer Toth, 2016, Image-Guided Endobronchial Ultrasound
  • Ronnarit Cheirsilp, Rebecca Bascom, Thomas Allen, Rickhesvar Mahraj and William E Higgins, 2016, Deformable image registration for multimodal lung-cancer staging
  • Patrick Byrnes and William E Higgins, 2016, Method for Endobronchial Video Parsing
  • William E Higgins, Ronnarit Cheirsilp, Xiaonan Zang and Patrick Byrnes, 2015, Multimodal system for the planning and guidance of bronchoscopy, pp. 941508-1--–941508-9
  • Xioanan Zang, Rebecca Bascom, Christopher R. Gilbert, Jennifer W. Toth and William E Higgins, , 3D Endobronchial Ultrasound Reconstruction and Analysis for Multimodal Image-Guided Bronchoscopy, SPIE, pp. 90400X-1 --- 90400X-12
  • Ronnarit Cheirsilp, Rebecca Bascom, Thomas W. Allen and William E Higgins, , 3D intrathoracic region definition and its application to PET-CT analysis, SPIE, pp. 90352J-1 --- 90352J-11
  • Patrick Byrnes and William E Higgins, , Construction of a multimodal CT-video chest model, SPIE, pp. 903607-1 --- 903607-11

Parts of Book

  • Xioanan Zang, Mikhail Breslav and William E Higgins, 2013, 3D Segmentation and Reconstruction of Endobronchial Ultrasound, SPIE
  • Ronnarit Cheirsilp and William E Higgins, 2013, Multimodal 3D PET/CT System for Bronchoscopic Procedure Planning, SPIE, Orlando, FL
  • Rahul Kare, Rebecca Bascom and William E Higgins, 2013, Technician-free system for image-guided bronchoscopy, SPIE

Journal Articles

  • William E Higgins, Xiaonan Zang, Patrick Byrnes, Ronnarit Cheirsilp, Trevor Kuhlengel, Jennifer Toth and Rebecca Bascom, 2019, "Route Planning for Predicting the Feasibility and Yield of Bronchoscopic Biopsy during Central-Chest Lymph Node Staging", Americian J. Respiratory and Critical Care Medicine
  • William E Higgins, Patrick Byrnes, Wennan Zhao, Trevor Kuhlengel, Jennifer Toth and Rebecca Bascom, 2019, "Virtual Reality Viewing of the Airway Mucosa: Bronchoscopic Video Analysis Fused with CT Images", Americian J. Respiratory and Critical Care Medicine
  • Patrick Byrnes and William E Higgins, 2019, "Efficient Bronchoscopic Video Summarization", IEEE Transactions on Biomedical Engineering, 66, (3), pp. 848-863
  • William E Higgins, Xiaonan Zang, Patrick Byrnes, Trevor Kuhlengel, Jennifer Toth and Rebecca Bascom, 2017, "Optimal Biopsy-Site Localization for Image-Guided Endobronchial Ultrasound", American J. Respiratory and Critical Care Medicine, 195
  • Xiaonan Zang, Rebecca Bascom, Christopher Gilbert, Jennifer Toth and William E Higgins, 2016, "Methods for 2D and 3D Endobronchial Ultrasound Image Segmentation", IEEE Trans. Biomedical Engineering, 63, (7)
  • William E Higgins, Xiaonan Zang, Ronnarit Cheirsilp, Patrick Byrnes, Trevor Kuhlengel, Jennifer Toth and Rebecca Bascom, 2016, "System for Multimodal Image-Guided Endobronchial Ultrasound: Human Pilot Study", Americian J. Respiratory and Critical Care Medicine, 193
  • William E Higgins, Ronnarit Cheirsilp, Xiaonan Zang, Patrick Byrnes, Trevor Kuhlengel, Jennifer Toth, Thomas Allen and Rebecca Bascom, 2016, "PET/CT Image Registration for Multimodal Bronchoscopic Procedure Planning and Guidance", Americian J. Respiratory and Critical Care Medicine, 193
  • Rahul Khare, Rebecca Bascom and William E Higgins, 2015, "Hands-Free System for Bronchoscopy Planning and Guidance", IEEE Trans. Biomedical Engineering, 62, (12), pp. 18
  • Ronnarit Cheirsilp, Rebecca Bascom, Thomas W. Allen and William E Higgins, 2015, "Thoracic Cavity Definition for 3D PET/CT Analysis and Visualization", Computers in Biology and Medicine, 62, (7), pp. 15
  • William E Higgins, Xiaonan Zang, Ronnarit Cheirsilp, Patrick Byrnes, Trevor Kuhlengel, Anne Dimmock, Thomas Allen, Christopher Gilbert, Rickhesvar Mahraj, Jennifer Toth and Rebecca Bascom, 2015, "Multimodal Image-Guided System for Bronchoscopy: Human Feasibility Study", Americian J. Respiratory and Critical Care Medicine, 191
  • William E Higgins, Ronnarit Cheirsilp, Trevor Kuhlengel, Thomas Allen, Rickhesvar Mahraj and Rebecca Bascom, 2015, "Computer-based 3D PET/CT Thoracic ROI Detection, Definition, and Visualization", Americian J. Respiratory and Critical Care Medicine, 191
  • William E Higgins, X. Zang, P. D. Byrnes, R. Cheirsilp, T. Kuhlengel, A. E. Dimmock, J. W. Toth, C. Gilbert and R. Bascom, 2014, "Multimodal Image-Guided Intervention System for Bronchoscopy and EBUS Fusion", American Journal of Respiratory and Critical Care Medicine, 189, pp. A2511
  • William E Higgins, R. Khare, D. C. Cornish, X. Zang, R. Cheirsilp, P. D. Byrnes, J. W. Toth, M. Reed and R. Bascom, 2014, "Technician-Free Image-Guided Bronchoscopy System: A Human Study", American Journal of Respiratory and Critical Care Medicine, 189, pp. A2512
  • William E Higgins, D. C. Higgins, D. C. Cornish, R. Khare, J. Toth, M. Reed and R. Bascom, 2014, "Sensor-based Bronchoscopy Guidance System: Human Studies", American Journal of Respiratory and Critical Care Medicine, 189, pp. A2513
  • Jason D. Gibbs, Michael W. Graham, Rebecca Bascom, Duane C. Cornish, Rahul Khare and William E Higgins, 2014, "Optimal procedure planning and guidance system for peripheral bronchoscopy", IEEE Trans. Biomedical Engineering, 61, (3), pp. 638-657
  • Scott M. Merritt, Rahul Khare, Rebecca Bascom and William E Higgins, 2013, "Real-time CT-Video registration for the continuous guidance of bronchoscopy", IEEE Transactions on Medical Imaging, 32, (8), pp. 1376-1396

Research Projects

  • August 2010 - December 2022, "Multimodal Image-Guided Intervention System for Lung-Cancer Diagnosis and Staging," (Sponsor: National Cancer Institute).
  • August 2010 - January 2015, "Multimodal Image-Guided Intervention System for Lung-Cancer Diagnosis and Staging," (Sponsor: National Cancer Institute).

Honors and Awards

Service

Service to Penn State:

Service to External Organizations:

 


 

About

The Department of Biomedical Engineering administers the undergraduate major in biomedical engineering, and is a part of the university-wide Intercollege Graduate Degree Program, offering both M.S. and Ph.D. degrees in Bioengineering. Our work combines traditional engineering principles with medicine and technology for the betterment of human health and society. 

Department of Biomedical Engineering

122 Chemical and Biomedical Engineering Building

The Pennsylvania State University

University Park, PA 16802-4400

Phone: 814-863-6614