Photo of William Higgins

William Higgins

Distinguished Professor

Affiliation(s):

  • School of Electrical Engineering and Computer Science
  • Electrical Engineering
  • Biomedical Engineering

209F Electrical Engineering West

weh2@psu.edu

814-865-0186

Research Website

Research Areas:

Biomedical Devices; Computational Science; Data Science and Artificial Intelligence; Signal and Image Processing

Interest Areas:

3D Medical Image Processing, Virtual Endoscopy, Image Processing, Computer Vision, Visualization

 
 

 

Education

Publications

Journal Articles

  • Xiaonan Zang, Ronnarit D Cheirsilp, Patrick Byrnes, Trevor Kuhlengel, Catherine Abendroth, Thomas Allen, Rickhesvar Mahraj, Jennifer Toth, Rebecca Bascom and William E Higgins, 2021, "Image-Guided EBUS Bronchoscopy System for Lung-Cancer Staging", Informatics in Medicine Unlocked
  • William E Higgins, Trevor Kuhlengel and Rebecca Bascom, 2021, "Automatic Procedure Planning for Comprehensive Bronchoscopic Lymph Node Staging", Americian J. Respiratory and Critical Care Medicine, 203, (May)
  • William E Higgins, Wennan Zhao, Danish Ahmad, Jennifer Toth and Rebecca Bascom, 2021, "Multimodal Virtual Bronchoscopic Guidance of Radial-Probe EBUS for Peripheral Nodule Biopsy: A Phantom Study", Americian J. Respiratory and Critical Care Medicine, 203, (May)
  • William E Higgins, Trevor Kuhlengel and Rebecca Bascom, 2020, "Automated 3D-CT-based Lymph Node Station Definition for the IASLC 8th edition Guidelines", Americian J. Respiratory and Critical Care Medicine, 201, (May), pp. A4447-A4448
  • Xiaonan Zang, Jason D Gibbs, Ronnarit Cheirsilp, Patrick Byrnes, Jennifer Toth, Rebecca Bascom and William E Higgins, 2019, "Optimal Route Planning for Image-Guided EBUS Bronchoscopy", Computers in Biology and Medicine, 112, pp. 103361
  • William E Higgins, Patrick Byrnes, Wennan Zhao, Trevor Kuhlengel, Jennifer Toth and Rebecca Bascom, 2019, "Virtual Reality Viewing of the Airway Mucosa: Bronchoscopic Video Analysis Fused with CT Images", Americian J. Respiratory and Critical Care Medicine, 199, pp. A2617-A2618
  • William E Higgins, Xiaonan Zang, Patrick Byrnes, Ronnarit Cheirsilp, Trevor Kuhlengel, Jennifer Toth and Rebecca Bascom, 2019, "Route Planning for Predicting the Feasibility and Yield of Bronchoscopic Biopsy during Central-Chest Lymph Node Staging", American J. Respiratory and Critical Care Medicine, 199, pp. A2346-A2347
  • Patrick Byrnes and William E Higgins, 2019, "Efficient Bronchoscopic Video Summarization", IEEE Transactions on Biomedical Engineering, 66, (3), pp. 848-863
  • William E Higgins, Xiaonan Zang, Patrick Byrnes, Trevor Kuhlengel, Jennifer Toth and Rebecca Bascom, 2017, "Optimal Biopsy-Site Localization for Image-Guided Endobronchial Ultrasound", American J. Respiratory and Critical Care Medicine, 195
  • Xiaonan Zang, Rebecca Bascom, Christopher Gilbert, Jennifer Toth and William E Higgins, 2016, "Methods for 2D and 3D Endobronchial Ultrasound Image Segmentation", IEEE Trans. Biomedical Engineering, 63, (7), pp. 1426-1439
  • William E Higgins, Xiaonan Zang, Ronnarit Cheirsilp, Patrick Byrnes, Trevor Kuhlengel, Jennifer Toth and Rebecca Bascom, 2016, "System for Multimodal Image-Guided Endobronchial Ultrasound: Human Pilot Study", Americian J. Respiratory and Critical Care Medicine, 193, pp. A4382-83
  • William E Higgins, Ronnarit Cheirsilp, Xiaonan Zang, Patrick Byrnes, Trevor Kuhlengel, Jennifer Toth, Thomas Allen and Rebecca Bascom, 2016, "PET/CT Image Registration for Multimodal Bronchoscopic Procedure Planning and Guidance", Americian J. Respiratory and Critical Care Medicine, 193, pp. A4381
  • Rahul Khare, Rebecca Bascom and William E Higgins, 2015, "Hands-Free System for Bronchoscopy Planning and Guidance", IEEE Trans. Biomedical Engineering, 62, (12), pp. 18
  • Ronnarit Cheirsilp, Rebecca Bascom, Thomas W. Allen and William E Higgins, 2015, "Thoracic Cavity Definition for 3D PET/CT Analysis and Visualization", Computers in Biology and Medicine, 62, (7), pp. 15
  • William E Higgins, Xiaonan Zang, Ronnarit Cheirsilp, Patrick Byrnes, Trevor Kuhlengel, Anne Dimmock, Thomas Allen, Christopher Gilbert, Rickhesvar Mahraj, Jennifer Toth and Rebecca Bascom, 2015, "Multimodal Image-Guided System for Bronchoscopy: Human Feasibility Study", Americian J. Respiratory and Critical Care Medicine, 191
  • William E Higgins, Ronnarit Cheirsilp, Trevor Kuhlengel, Thomas Allen, Rickhesvar Mahraj and Rebecca Bascom, 2015, "Computer-based 3D PET/CT Thoracic ROI Detection, Definition, and Visualization", Americian J. Respiratory and Critical Care Medicine, 191
  • William E Higgins, X. Zang, P. D. Byrnes, R. Cheirsilp, T. Kuhlengel, A. E. Dimmock, J. W. Toth, C. Gilbert and R. Bascom, 2014, "Multimodal Image-Guided Intervention System for Bronchoscopy and EBUS Fusion", American Journal of Respiratory and Critical Care Medicine, 189, pp. 1
  • William E Higgins, R. Khare, D. C. Cornish, X. Zang, R. Cheirsilp, P. D. Byrnes, J. W. Toth, M. Reed and R. Bascom, 2014, "Technician-Free Image-Guided Bronchoscopy System: A Human Study", American Journal of Respiratory and Critical Care Medicine, 189, pp. 1
  • William E Higgins, D. C. Higgins, D. C. Cornish, R. Khare, J. Toth, M. Reed and R. Bascom, 2014, "Sensor-based Bronchoscopy Guidance System: Human Studies", American Journal of Respiratory and Critical Care Medicine, 189, pp. 1
  • Jason D. Gibbs, Michael W. Graham, Rebecca Bascom, Duane C. Cornish, Rahul Khare and William E Higgins, 2014, "Optimal procedure planning and guidance system for peripheral bronchoscopy", IEEE Trans. Biomedical Engineering, 61, (3), pp. 20
  • Scott M. Merritt, Rahul Khare, Rebecca Bascom and William E Higgins, 2013, "Real-time CT-Video registration for the continuous guidance of bronchoscopy", IEEE Transactions on Medical Imaging, 32, (8), pp. 1376-1396

Conference Proceedings

  • Qi Chang, Rebecca Bascom, Jennifer Toth, Danish Ahmad and William E Higgins, 2020, "Autofluorescence Bronchoscopy Video Analysis for Lesion Frame Detection", pp. 1556-1559
  • Patrick Byrnes and William E Higgins, 2020, "Multi-Frame CT-Video Registration for 3D Airway-Wall Analysis", pp. 1638-1641

Other

  • Xioanan Zang, Mikhail Breslav and William E Higgins, 2013, "3D Segmentation and Reconstruction of Endobronchial Ultrasound", 8675
  • Ronnarit Cheirsilp and William E Higgins, 2013, "Multimodal 3D PET/CT System for Bronchoscopic Procedure Planning", 8670
  • Rahul Kare, Rebecca Bascom and William E Higgins, 2013, "Technician-free system for image-guided bronchoscopy", 8671

Research Projects

Honors and Awards

  • Inventor of the Year, Invent Penn State, October 2019 - October 2019
  • Senior Member, National Academy of Inventors, February 2019 - February 2019

Service

Service to Penn State:

Service to External Organizations:

 


 

About

The Department of Biomedical Engineering administers the undergraduate major in biomedical engineering, and is a part of the university-wide Intercollege Graduate Degree Program, offering both M.S. and Ph.D. degrees in Bioengineering. Our work combines traditional engineering principles with medicine and technology for the betterment of human health and society. 

Department of Biomedical Engineering

122 Chemical and Biomedical Engineering Building

The Pennsylvania State University

University Park, PA 16802-4400

Phone: 814-863-6614

Email: bme@engr.psu.edu