Welcome to the Transformative Biomaterials and Biotechnology Lab (TBBL) at The Penn State University. Our research interests are to investigate a methodology for functional biomaterial development and use biomaterials as a tool to solve unmet clinical problems.

Currently, our research projects include: 1) Methodology for new biomaterial development; 2) soft and hard tissue engineering; 3) cancer drug delivery and imaging; 4) stem cell/biomaterial interactions; 5) micro-/nano-medical device fabrication; 6) biosensing.


Upcoming Events





Congratulation to Dr. Gloria Kim and the team for the paper regarding CAR-T cell-mediated drug delivery for bran cancer treatment accepted by Bioactive Materials.


Congratulation to Dr. Jinshan Guo for his paper regarding "Citrate-based tannin-bridged bone composites for lumbar fusion" accepted by Advanced Functional Materials.


Congratulation to Sarah Knappman for winning a research scholarship from Society for Women Engineers (SWE) to support her research in Fall 2019.


Congratulation to PhD student, Chuying Ma for winning the Harold K. Schilling Dean's Graduate Scholarship. This scholarship recognizes Chuying's outstanding research on stem cells and orthopedic biomaterials.


Congratulation to Sarah Knappman, an undergraduate researcher in Yang lab, to receive David and Shirley Wormley Scholarship.


Dr. Yang was elected to National Academy of Inventors Fellow (NAI Fellow). NAI Press Release. PSU News


Congratulation to Chuying for her metabonegeneic citrate biomaterial paper accepted by PNAS. (News Link)


Dr. Yang was selected to receive Penn State Engineering Alumni Society (PSEAS) Outstanding Research Award.


TBBL welcomes Dr. Su Yan joining our research team.


Congratulation to Sarah Knappman and Yu-Chi Huang for winning 2018 Fall College of Engineering Research Initiative (CERI) scholarship.


TBBL celebrates the graduation of Dingying and Jimin. Congratulation to Dr. Dingying Shan and Dr. Jimin Peter Kim.


Congratulation, Dingying's paper regarding dual-imaging enabled biodegradable electroactive polymers was accepted by "Advanced Functional Materials".


Dr. Yang received a R01 grant from NIH/NIAMS to study citrate metabonegenesis regulation for new orthopedic biomaterial design.


Adv Mater 2014 (click polymer)
Adv Mater 2014 (BPLP-PLA)

PNAS 2009 (BPLP)
ACS Nano 2014 (In situ endothelium repair)

Chemical Science 2017 (Fluorescent sensor for cystic fibrosis diagnosis)

Acta Biomaterialia
2017 (Complete story of citrate fluorescence mechanism)

Advanced Functional Materials 2018 (Dual imaging enabled multifunctional elastomers)
Small 2017 (Immune cell-mediated drug delivery)

PNAS 2018 (Citrate Metabonegenic Regulation and Bone Regeneration)

Positions Available

Postdoctoal fellow position (Please send your CV to Dr Jian Yang via email: jxy30@psu.edu to inquire the availability of positions.

PhD candidates: We are always seeking highly self-motivated and intelligent PhD students to work on biomaterials, stem cells, and tissue engineering projects. Students who have a strong background in any of the following disciplines: bioengineering, chemical engineering, material science engineering, chemistry, biology are all welcome to apply.

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